mysql - handling bigdata from excel in php -

this opinion based question. let have excel file 4k row , 50 column. have handle file in step step. here mention steps

1. validate every field of every row. (here mysql query run checking database related validation)

2. if data valid have save data in 3 table , update 1 table
   example
   column 1-20 insert in table_1
   column 21-40 insert in table_2
   column 41-50 insert in table_3
   update table_1 last insert id of table_2 , table_3

now want know best practice handle big data. suggestion compatible php, cakephp or laravel

now want know best practice handle big data.

as handle other "big data" well: read , process in chunks of given size each chunk fits limitations of system.